ea0029p997 | Growth hormone IGF axis - basic | ICEECE2012
Thankamony A.
, Capalbo D.
, Heywood J.
, Williams R.
, Ong K.
, Dunger D.
, Simpson H.
Background: GH replacement during the childhood-adult transition period is important for somatic maturation. The aim of the study was to explore the factors influencing IGF1 response to GH during transition.Methods: KIMS (Pfizer International Metabolic Study) database in UK was interrogated, and 98 patients (55 male, median age 20.7 years (15.725.8)) with childhood-onset GH deficiency (Co-GHD), who were started on adult dose of GH during transition...